Not all patients with CLL need therapy. Despite all current developments, the iwCLL nevertheless suggests watchful observation for individuals with asymptomatic condition.86 This suggestion relies on no less than two randomized trials comparing observation to either chlorambucil monotherapy or fludarabine, cyclophosphamide and rituximab (FCR).103,104 Equally trials concluded that earl... https://edwinkapds.anchor-blog.com/12762625/facts-about-mbl77-revealed