Contraindicated (1)pentobarbital will minimize the level or result of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Women of all ages must not decide on estradiol valerate/dienogest as their contraceptive even though utilizing strong CYP3A4 inducers as a consequence of probable lower in contraceptive efficacy. pentobarbital wil... https://rebeccas232wlv8.scrappingwiki.com/user