Pentobarbital will decrease the level or effect of abemaciclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of abemaciclib with strong CYP3A4 inducers reduces plasma concentration of abemaciclib and its metabolites. Temblores y espasmos musculares: estos aún pueden ser el resultado de contracciones musculares esqueléticas refl... https://donovanqnjeb.answerblogs.com/30245553/se-desconoce-datos-sobre-cuáles-son-las-alternativas-al-pentobarbital