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The pipecolate location of rapamycin structure seems essential for rapamycin-binding to FKBP12. This move is necessary for further binding of rapamycin towards the mTOR kinase, which can be The real key enzyme in lots of biological actions of rapamycin.[forty six] Although the new generation of mTOR inhibitors hold wonderful promise https://casso520ejn3.blogpayz.com/profile

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