Pentobarbital decreases effects of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Coadministration of CYP3A4 inducers could decrease sufentanil amounts and efficacy, possibly precipitating withdrawal syndrome in clients who've formulated Bodily dependence to sufentanil. Discontinuation of concomitantly used CYP3A4 induc... https://beauwobrd.madmouseblog.com/2738141/the-best-side-of-sodium-pentobarbital-mouse